Blar i Publikasjoner fra CRIStin - SINTEF AS på tittel

Viser treff 4913-4932 av 5674

    • Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors 

      Anthiya, Shubaash; Oztürk, Süleyman Can; Yanik, Hamdullah; Tavukcuoglu, Ece; Sahin, Adem; Datta, Dhrubajyoti; Charisse, Klaus; Álvarez, David Moreira; Loza, María Isabel; Calvo, Alfonso; Sulheim, Einar; Loevenich, Simon; Klinkenberg, Geir; Schmid, Ruth Baumberger; Manoharan, Muthiah; Esendağlı, Güneş; Jose Alonso, Maria (Peer reviewed; Journal article, 2023)
      K-RAS is a highly relevant oncogene that is mutated in approximately 90% of pancreatic cancers and 20–25% of lung adenocarcinomas. The aim of this work was to develop a new anti-KRAS siRNA therapeutic strategy through the ...

    • Targeting OGG1 arrests cancer cell proliferation by inducing replication stress 

      Visnes, Torkild; Benitez-Buelga, Carlos; Cázares-Körner, Armando; Sanjiv, Kumar; Hanna, Bishoy M F; Mortusewicz, Oliver; Rajagopal, Varshni; Albers, Julian J.; Hagey, Daniel W.; Bekkhus, Tove; Eshtad, Saeed; Baquero, Juan Miguel; Masuyer, Geoffrey; Wallner, Olov; Müller, Sarah; Pham, Therese; Gokturk, Camilla; Rasti, Azita; Suman, Sharda; Torres-Ruiz, Raúl; Sarno, Antonio; Wiita, Elisée; Homan, Evert; Karsten, Stella; Marimuthu, Karthick; Michel, M; Koolmeister, Tobias; Scobie, Martin; Loseva, Olga; Almlöf, Ingrid; Unterlass, Judith Edda; Pettke, Aleksandra; Boström, Johan; Pandey, Monica; Gad, Helge; Herr, Patrick; Jemth, Ann-Sofie; El Andaloussi, Samir; Kalderén, Christina; Rodriguez-Perales, Sandra; Benítez, Javier; Krokan, Hans Einar; Altun, Mikael; Stenmark, Pål; Berglund, Ulrika Warpman; Helleday, Thomas (Peer reviewed; Journal article, 2020)
      Abstract Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e.g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies ...

    • Task-Technology Fit in Manufacturing: Examining Human-Machine Symbiosis Through a Configurational Approach 

      Mikalef, Patrick; Torvatn, Hans Yngvar; Arica, Emrah (Chapter; Peer reviewed, 2019)
      With the last few years seeing an increased introduction of technological innovations in factories, one of the most pressing issues is how these technologies can be deployed to optimally support the activities of professionals ...

    • Tasks, information models and visual prototypes for local leaders at the TYR training exercise 

      Nilsson, Erik Gösta (Research report, 2010)
      In this report we look into tasks for the local leader in the police at the TYR exercise, and describe both the tasks and the information involved when performing them. The identification of tasks and the further analysis ...

    • TASS5 for Trondheim 

      Meland, Solveig; Skjetne, Eirik; Tørset, Trude; Malmin, Olav Kåre (SINTEF rapport;A05100, Research report, 2006)
      Denne rapporten inneholder dokumentasjon av TASS versjon 5 for Trondheim. Den nye versjonen av modellen representerer en oppgradering av tidligere transportmodell, TASS versjon 4. Endringen består i at vesentlige deler av ...

    • A taxonomy for autonomy in industrial autonomous mobile robots including autonomous merchant ships 

      Rødseth, Ørnulf Jan; Vagia, Marialena (Peer reviewed; Journal article, 2020)
      The concept of autonomous mobile robots (AMR) has gained much popularity in recent years, particularly in commercial settings where the name industrial autonomous mobile robot (IAMR) is proposed. In addition to automatic ...

    • A Taxonomy for Engineering Change Management in Complex ETO Firms 

      Arica, Emrah; Bakås, Ottar; Sriram, Pavan (Peer reviewed; Journal article, 2020)
      In this paper, we study a specific type of Engineer-to-Order (ETO) firms called Complex ETO characterized by one-of-a-kind products with high complexity and low volumes. Such firms are at high risk of encountering significant ...

    • A taxonomy of inter-team coordination mechanisms in large-scale agile 

      Berntzen, Marthe; Hoda, Rashina; Moe, Nils Brede; Stray, Viktoria (Peer reviewed; Journal article, 2022)
      In large-scale agile software development, many teams work together to achieve overarching project goals. The more teams, the greater the coordination requirements. Despite the growing popularity of large-scale agile, ...

    • Tåler byggene mer regn nå? 

      Nygård, Ragnhild Lokna (Journal article, 2020)
      Fuktinntrengning i bygg har alltid vært en utfordring i Norge. Med hyppigere og mer intens nedbør i vente blir det viktigere enn noen gang å bygge med tanke på det norske klimaet.

    • Teacher-student approach for lung tumor segmentation from mixed-supervised datasets 

      Fredriksen, Vemund; Sevle, Svein Ole M.; Pedersen, André; Langø, Thomas; Kiss, Gabriel; Lindseth, Frank (Peer reviewed; Journal article, 2022)
      Purpose: Cancer is among the leading causes of death in the developed world, and lung cancer is the most lethal type. Early detection is crucial for better prognosis, but can be resource intensive to achieve. Automating ...

    • Team Autonomy in Large-Scale Agile 

      Moe, Nils Brede; Dahl, Bjørn Haug; Stray, Viktoria; Karlsen, Lina Sund; Schjødt-Osmo, Stine (Proceeding of the 52nd Hawaii International Conference on System Sciences (HICSS 2019);, Chapter; Peer reviewed, 2019)
      Large-scale software development is increasingly making use of agile practices. In large-scale projects, a team needs to align with other teams and the rest of the organization. This has been shown to threaten team autonomy, ...

    • Team Performance in Software Development: Research Results versus Agile Principles 

      Dingsøyr, Torgeir; Fægri, Tor Erlend; Dybå, Tore; Haugset, Børge; Lindsjørn, Yngve (Journal article, 2016)

    • Team-external coordination in large‐scale software development projects 

      Sablis, Aivars; Šmite, Darja; Moe, Nils Brede (Peer reviewed; Journal article, 2020)
      High‐quality work is said to depend on team abilities. However, teams working in large‐scale projects often do not have all expertise to complete their tasks, which are also highly interdependent. Therefore, teams need to ...

    • Teamwork Quality and Project Success in Software Development: A Survey of Agile Development Teams 

      Lindsjørn, Yngve; Sjøberg, Dag; Dingsøyr, Torgeir; Bergersen, Gunnar R.; Dybå, Tore (Journal article, 2016)
      Small, self-directed teams are central in agile development. This article investigates the effect of team- work quality on team performance, learning and work satisfaction in agile software teams, and whether this effect ...

    • Teamwork Quality and Team Performance: Exploring Differences Between Small and Large Agile Projects 

      Lindsjørn, Yngve; Bergersen, Gunnar R.; Dingsøyr, Torgeir; Sjøberg, Dag (Chapter, 2018)
      Agile principles were originally developed for small projects but are now widely used in larger projects with hundreds of developers. Teamwork quality is essential in any development work, but how does teamwork quality ...

    • Technical and Environmental Properties of Recycled Aggregates Produced from Concrete Sludge and Excavation Materials 

      Adomako, Solomon; Engelsen, Christian John; Døssland, Line Teigen; Danner, Tobias Alexander; Thorstensen, Rein Terje (Peer reviewed; Journal article, 2023)
      This study presents a Re-Con Zero dry washing technology used to produce recycled aggregates from concrete sludge (RCZ) and combined as a feedstock in wet recycling excavation materials (EM) for unbound applications. A ...

    • Technical and environmental viability of a European CO2 EOR system 

      Thorne, Rebecca Jayne; Sundseth, Kyrre; Bouman, Evert; Czarnowska, Lucyna; Mathisen, Anette; Skagestad, Ragnhild; Stanek, Wojciech; Pacyna, Jozef M; Pacyna, Elisabeth G (Peer reviewed; Journal article, 2019)
      Captured CO2 from large industrial emitters may be used for enhanced oil recovery (EOR), but as of yet there are no European large-scale EOR systems. Recent implementation decisions for a Norwegian carbon capture and storage ...

    • Technical Support Agreement for LAV TUA 

      Helle, Espen; Johansen, Gorm Idar; Mathisen, Geir (Research report, 2010)
      This report describes the work carried out in the period January 2009 – February 2010 by SINTEF under the maintenance contract with NAMSA. Oppdragsgiver: NAMSA

    • Technical-, social- and process debt in large-scale agile: An exploratory case-study 

      Martini, Antonio; Stray, Viktoria; Moe, Nils Brede (Peer reviewed; Journal article, 2019)
      Large-scale agile projects bring inter-teams interaction challenges. Teams need to be autonomous, but often crosscutting concerns affect many teams. If the teams fail to collaborate on these concerns, the negative effects ...

    • Techniques for airflow measurements to determine the real efficiency of heat recovery in ventilation systems 

      Rønneseth, Øystein; Liu, Peng; Alonso, Maria Justo; Mathisen, Hans Martin (Conference object; Journal article; Peer reviewed, 2019)
      Heat recovery in ventilation is essential to reduce energy use and thus mitigate greenhouse gas emissions from the building sector. Heat recovery efficiency of at least 80% in new buildings is required according to Norwegian ...