• Validation of Geant4 for silicon microdosimetry in heavy ion therapy 

      Bolst, David; Gautelli, Susanna; Tran, Linh T.; Davis, Jeremy; Chartier, Lachlan; Prokopovich, Dale A.; Pogossov, Alex; Reinhard, Mark I.; Petasecca, Marco; Lerch, Michael L.F.; Matsufuji, Naruhiro; Povoli, Marco; Kok, Angela; Summanwar, Anand; Jackson, Michael; Rosenfeld, Anatoly B. (Journal article; Peer reviewed, 2019)
      Microdosimetry is a particularly powerful method to estimate the relative biological effectiveness (RBE) of any mixed radiation field. This is particularly convenient for therapeutic heavy ion therapy (HIT) beams, referring ...
    • Validation of linear energy transfer computed in a Monte Carlo dose engine of a commercial treatment planning system 

      Wagenaar, David; Tran, Linh T.; Meijers, Arturs; Marmitt, Gabriel Guterres; Souris, Kevin; Bolst, David; Povoli, Marco; Kok, Angela; Traneus, Erik; Van Goethem, Marc-Jan; Langendijk, Johannes A.; Rosenfeld, Anatoly B.; Both, Stefan (Journal article; Peer reviewed, 2019)
      The relative biological effectiveness (RBE) of protons is highly variable and difficult to quantify. However, RBE is related to the local ionization density, which can be related to the physical measurable dose weighted ...