dc.contributor.author | Nitter, Therese Bergh | |
dc.contributor.author | Hilt, Bjørn | |
dc.contributor.author | Svendsen, Kristin V Hirsch | |
dc.contributor.author | Buhagen, Morten | |
dc.contributor.author | Dahlman, Hans Jørgen | |
dc.contributor.author | Øvrevik, Johan | |
dc.contributor.author | Refsnes, Magne Arnold | |
dc.contributor.author | Jørgensen, Rikke Bramming | |
dc.date.accessioned | 2022-01-25T09:57:40Z | |
dc.date.available | 2022-01-25T09:57:40Z | |
dc.date.issued | 2021 | |
dc.identifier.isbn | 978-82-536-1728-2 | |
dc.identifier.issn | 2387-4295 | |
dc.identifier.uri | https://hdl.handle.net/11250/2839148 | |
dc.description.abstract | During the winter in Scandinavian countries, up to 90% of traffic-related particulate matter (PM) is from non-exhaust emissions sources such as asphalt wear. Measures to reduce urban PM have focused mainly on exhaust emissions, while the contribution from asphalt has received less attention. In vitro studies suggest that the composition of asphalt can affect the inflammatory potential of road dust. Using a whole-body human exposure chamber, we have explored whether different stone materials used in Norwegian asphalt impose different inflammatory reactions in plasma of healthy volunteers. Our results show no acute increases in the inflammatory markers SP-D, P- selectin, or CC16. However, quartz diorite induced an apparent increase in ICAM-1, not seen for rhomb porphyry or placebo dust (lactose). Although this did not reach statistical significance, it resembles previously observed fibrinogen-effects, and may suggest that different types of stone minerals provoke different inflammatory reactions in humans compared to placebo dust. | |
dc.language.iso | eng | |
dc.publisher | SINTEF Academic Press | |
dc.relation.ispartof | Healthy Buildings 2021 – Europe. Proceedings of the 17th International Healthy Buildings Conference 21–23 June 2021 | |
dc.relation.ispartofseries | SINTEF Proceedings;9 | |
dc.rights | CC BY 4.0 | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Inflammatory effects of exposure to different stone types used in Norwegian asphalt | |
dc.type | Chapter | |
dc.type | Peer reviewed | |
dc.type | Conference object | |
dc.description.version | publishedVersion | |
dc.rights.holder | © 2021 The Authors. Published by SINTEF Academic Press. | |
dc.subject.nsi | VDP::Teknologi: 500 | |