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dc.contributor.authorMossige, Endre Joachim
dc.contributor.authorEdvardsen, Bente
dc.contributor.authorJensen, Atle
dc.contributor.authorMielnik, Michal Marek
dc.date.accessioned2020-02-27T10:20:27Z
dc.date.available2020-02-27T10:20:27Z
dc.date.created2019-03-29T11:57:13Z
dc.date.issued2019
dc.identifier.issn1613-4982
dc.identifier.urihttp://hdl.handle.net/11250/2644133
dc.descriptionPostprint version of published article. The final publication is available at Springer via http://dx.doi.org/10.1007/s10404-019-2209-ynb_NO
dc.description.abstractAn inherent problem with microfluidic filters is the tendency to clog, especially when applied to cells due to their geometrical complexity, deformability, and tendency to adhere to surfaces. In this work, we handle live algal cells of high complexity without signs of clogging, achieved by exploiting hydrodynamic interactions around trilobite-shaped filtration units. To characterize the influence of cell complexity on the separation and concentration mechanisms, we compare the hydrodynamic interactions to those of synthetic, rigid microparticles. We discover that simple rolling along the filter structures, which prevents clogging for particles, cannot be applied to cells. Instead, we find that inertial effects must be employed to minimize the filter interactions and that this modification leads to only a minor reduction in device performance.nb_NO
dc.language.isoengnb_NO
dc.publisherSpringernb_NO
dc.subjectMicrofluidic filtersnb_NO
dc.subjectCloggingnb_NO
dc.subjectAlgal cellsnb_NO
dc.titleA tunable, microfluidic filter for clog‑free concentration and separation of complex algal cellsnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionacceptedVersionnb_NO
dc.source.volume23nb_NO
dc.source.journalMicrofluidics and Nanofluidicsnb_NO
dc.source.issue56nb_NO
dc.identifier.doihttps://doi.org/10.1007/s10404-019-2209-y
dc.identifier.cristin1688827
cristin.unitcode7401,90,31,0
cristin.unitnameMicrosystems and Nanotechnology
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1


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