• Biophysical Characterization of Viral and Lipid-Based Vectors for Vaccines and Therapeutics with Light Scattering and Calorimetric Techniques 

      Markova, Natalia; Cairns, Stefan; Jankevics-Jones, Hanna; Kaszuba, Michael; Caputo, Fanny; Parot, Jérémie (Peer reviewed; Journal article, 2022)
      Novel vaccine platforms for delivery of nucleic acids based on viral and non-viral vectors, such as recombinant adeno associated viruses (rAAV) and lipid-based nanoparticles (LNPs), hold great promise. However, they pose ...
    • Quality assessment of LNP-RNA therapeutics with orthogonal analytical techniques 

      Parot, Jérémie; Mehn, Dora; Jankevics-Jones, Hanna; Markova, Natalia; Carboni, Michele; Olaisen, Camilla; Hoel, Andrea Draget; Sigfúsdóttir, Margrét S.; Meier, Florian; Drexel, Roland; Vella, Gabriella; Mcdonagh, Birgitte Hjelmeland; Hansen, Terkel; Bui, Huong; Klinkenberg, Geir; Visnes, Torkild; Gioria, Sabrina; Urban-Lopez, Patricia; Prina-Mello, Adriele; Borgos, Sven Even F.; Caputo, Fanny; Calzolai, Luigi (Peer reviewed; Journal article, 2024)
      The availability of analytical methods for the characterization of lipid nanoparticles (LNPs) for in-vivo intracellular delivery of nucleic acids is critical for the fast development of innovative RNA therapies. In this ...