Mucociliary clearance is humidity dependent–contrary to common belief

Abstract

Efficient mucociliary clearance (MCC) is a precondition for the moistening capacity of human noses. A review of the literature reveals that only young and healthy individuals can maintain efficient nasal MCC in low ambient humidity. Aging, concomitant diseases and stress factors, all diminish MCC and therefore the ability of maintaining homeostasis of the airways. In an aging population this finding calls for action. We cannot change the outdoor climate nor the physical laws that cause indoor dryness. But we must take responsibility for the anthropogenic indoor climate and its undesired consequences.