Blar i SINTEF Industri på emneord "Ultrasound"
Viser treff 1-6 av 6
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Effect of acoustic cluster therapy (ACT®) combined with chemotherapy in a patient-derived xenograft mouse model of pancreatic cancer
(Peer reviewed; Journal article, 2022)Pancreatic ductal adenocarcinomas respond poorly to chemotherapy, in part due to the dense tumor stroma that hinders drug delivery. Ultrasound (US) in combination with microbubbles has previously shown promise as a means ... -
Effect of ultrasound on the vasculature and extravasation of nanoscale particles imaged in real time
(Journal article; Peer reviewed, 2019)Ultrasound and microbubbles have been found to improve the delivery of drugs and nanoparticles to tumor tissue. To obtain new knowledge on the influence of vascular parameters on extravasation and to elucidate the effect ... -
Multi-modal characterization of vasculature and nanoparticle accumulation in five tumor xenograft models
(Peer reviewed; Journal article, 2018)Preclinical research has demonstrated that nanoparticles and macromolecules can accumulate in solid tumors due to the enhanced permeability and retention effect. However, drug loaded nanoparticles often fail to show increased ... -
Sonopermeation Enhances Uptake and Therapeutic Effect of Free and Encapsulated Cabazitaxel
(Peer reviewed; Journal article, 2021)Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and, thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to improve delivery to tumors, enhancing ... -
Ultrasound intensified CO2 desorption from pressurized loaded monoethanolamine solutions. I. parameters investigation and modelling
(Peer reviewed; Journal article, 2018)CO2 stripping from loaded monoethanolamine (MEA) aqueous solutions intensified by means of ultrasound was investigated in a lab-scale kettle reboiler with both gas and liquid continuous operations. The reboiler operating ... -
Ultrasound-Mediated Delivery of Chemotherapy into the Transgenic Adenocarcinoma of the Mouse Prostate Model
(Peer reviewed; Journal article, 2020)Ultrasound (US) in combination with microbubbles (MB) has had promising results in improving delivery of chemotherapeutic agents. However, most studies are done in immunodeficient mice with xenografted tumors. We used two ...