Blar i SINTEF Industri på forfatter "Vandebriel, Rob J."
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A comparative biodistribution study of polymeric and lipid-based nanoparticles
Åslund, Andreas; Vandebriel, Rob J.; Caputo, Fanny; de Jong, Wim H.; Delmaar, Christiaan; Hyldbakk, Astrid; Rustique, Emilie; Schmid, Ruth Baumberger; Snipstad, Sofie; Texier, Isabelle; Vernstad, Kai; Borgos, Sven Even F. (Peer reviewed; Journal article, 2022)Biodistribution of nanoencapsulated bioactive compounds is primarily determined by the size, shape, chemical composition and surface properties of the encapsulating nanoparticle, and, thus, less dependent on the physicochemical ... -
A Decision Support System for preclinical assessment of nanomaterials in medical products: the REFINE DSS
Zabeo, Alex; Rosada, Fabio; Pizzol, Lisa; Caputo, Fanny; Borgos, Sven Even F.; Parot, Jérémie; Geertsma, Robert; Pouw, Joost Jacob; Vandebriel, Rob J.; Moreno, Oihane Ibarrola; Hristozov, Danail (Peer reviewed; Journal article, 2022)The application of nanomaterials in medicine has led to novel pharmaceuticals and medical devices that have demonstrated a strong potential for increasing the efficacy/performance and safety of therapeutic and diagnostic ... -
Physiologically based pharmacokinetic modeling of intravenously administered nanoformulated substances
Minnema, Jordi; Borgos, Sven Even F.; Liptrott, Neill; Vandebriel, Rob J.; Delmaar, Christiaan (Peer reviewed; Journal article, 2022)The use of nanobiomaterials (NBMs) is becoming increasingly popular in the field of medicine. To improve the understanding on the biodistribution of NBMs, the present study aimed to implement and parametrize a physiologically ... -
Standardization of an in vitro assay matrix to assess cytotoxicity of organic nanocarriers: a pilot interlaboratory comparison
Eder, Kai Moritz; Marzi, Anne; Wågbø, Ane Marit; Vermeulen, Jolanda P.; de la Fonteyne-Blankestijn, Liset J. J.; Rösslein, Matthias; Ossig, Rainer; Klinkenberg, Geir; Vandebriel, Rob J.; Schnekenburger, Jürgen (Peer reviewed; Journal article, 2022)Nanotechnologies such as nanoparticles are established components of new medical devices and pharmaceuticals. The use and distribution of these materials increases the requirement for standardized evaluation of possible ...