Blar i Publikasjoner fra CRIStin på tidsskrift "Nucleic Acids Research"
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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
(Peer reviewed; Journal article, 2020)Abstract Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e.g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies ... -
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress
(Peer reviewed; Journal article, 2020)Abstract Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e.g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies ...