Browsing Publikasjoner fra CRIStin by Author "Saei, Amir Ata"

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Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds

Peuget, Sylvain; Zhu, J; Sanz, Gema; Singh, Madhurendra; Gaetani, Massimiliano; Chen, Xinsong; Shi, Yao; Saei, Amir Ata; Visnes, Torkild; Lindström, Mikael; Rihani, A; Moyano-Galceran, Lidia; Carlson, Joseph W.; Hjerpe, Elisabeth; Joneborg, Ulrika; Lehti, Kaisa; Hartman, Johan; Helleday, Thomas; Zubarev, Roman A.; Selivanova, Galina (Peer reviewed; Journal article, 2020)

Identification of the molecular mechanism of action (MoA) of bioactive compounds is a crucial step for drug development but remains a challenging task despite recent advances in technology. In this study, we applied ...