• The relative biological effectiveness for carbon, nitrogen and oxygen ion beams using passive and scanning techniques evaluated with fully 3D silicon microdosimeters 

      Tran, Linh T.; Bolst, David; Guatelli, S.; Pogossov, A.; Petasecca, Marco; Lerch, Michael L.F.; Chartier, Lachlan; Prokopovich, Dale A.; Reinhard, Mark I.; Povoli, Marco; Kok, Angela; Perevertaylo, Vladimir I.; Matsufuji, Naruhiro; Kanai, T; Jackson, Michael; Rosenfeld, Anatoly B. (Journal article; Peer reviewed, 2018)
      Background: The aim of this study was to measure the microdosimetric distributions of a carbon pencil-beam scanning (PBS) and passive scattering system as well as to evaluate the relative biological effectiveness (RBE) of ...
    • Thin Silicon Microdosimeter utilizing 3D MEMS Fabrication Technology: Charge Collection Study and its application in mixed radiation fields 

      Tran, Linh T.; Chartier, Lachlan; Prokopovich, Dale A.; Bolst, David; Povoli, Marco; Summanwar, Anand; Kok, Angela; Pogossov, A.; Petasecca, Marco; Guatelli, S.; Reinhard, Mark I.; Lerch, Michael; Nancarrow, Mitchell; Matsufuji, Naruhiro; Jackson, Michael; Rosenfeld, Anatoly B. (Journal article; Peer reviewed, 2017)
      New 10-μm-thick silicon microdosimeters utilizing 3-D technology have been developed and investigated in this paper. The TCAD simulations were carried out to understand the electrical properties of the microdosimeters’ ...
    • Validation of Geant4 for silicon microdosimetry in heavy ion therapy 

      Bolst, David; Gautelli, Susanna; Tran, Linh T.; Davis, Jeremy; Chartier, Lachlan; Prokopovich, Dale A.; Pogossov, Alex; Reinhard, Mark I.; Petasecca, Marco; Lerch, Michael L.F.; Matsufuji, Naruhiro; Povoli, Marco; Kok, Angela; Summanwar, Anand; Jackson, Michael; Rosenfeld, Anatoly B. (Journal article; Peer reviewed, 2019)
      Microdosimetry is a particularly powerful method to estimate the relative biological effectiveness (RBE) of any mixed radiation field. This is particularly convenient for therapeutic heavy ion therapy (HIT) beams, referring ...
    • Validation of linear energy transfer computed in a Monte Carlo dose engine of a commercial treatment planning system 

      Wagenaar, David; Tran, Linh T.; Meijers, Arturs; Marmitt, Gabriel Guterres; Souris, Kevin; Bolst, David; Povoli, Marco; Kok, Angela; Traneus, Erik; Van Goethem, Marc-Jan; Langendijk, Johannes A.; Rosenfeld, Anatoly B.; Both, Stefan (Journal article; Peer reviewed, 2019)
      The relative biological effectiveness (RBE) of protons is highly variable and difficult to quantify. However, RBE is related to the local ionization density, which can be related to the physical measurable dose weighted ...