Browsing SINTEF Open by Author "Schmid, Ruth"

Now showing items 1-8 of 8

    • Archaeal tetraether lipid coatings - A strategy for the development of membrane analog spacer systems for the site-specific functionalization of medical surfaces 

      Liefeith, Klaus; Frant, Marion; Muller, Ute; Stenstad, Per Martin; Johnsen, Heidi; Schmid, Ruth (Peer reviewed; Journal article, 2018)
      The primary goal of our investigation was the development of a versatile immobilization matrix based on archaeal tetraether lipids that meets the most important prerequisites to render an implant surface bioactive by binding ...

    • Cytotoxicity of poly(Alkyl cyanoacrylate) nanoparticles 

      Sulheim, Einar; Iversen, Tore Geir; To, Vu; Klinkenberg, Geir; Sletta, Håvard; Schmid, Ruth; Hatletveit, Anne Rein; Wågbø, Ane Marit; Sundan, Anders; Skotland, Tore; Sandvig, Kirsten; Mørch, Ýrr Asbjørg (Peer reviewed; Journal article, 2017)
      Although nanotoxicology has become a large research field, assessment of cytotoxicity is often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and should, preferentially, be evaluated ...

    • Delivering the power of nanomedicine to patients today 

      Germain, Matthieu; Caputo, Fanny; Metcalfe, Su; Tosi, Giovanni; Spring, Kathleen; Åslund, Andreas K.O.; Pottier, Agnes; Schiffelers, Raymond; Ceccaldi, Alexandre; Schmid, Ruth (Peer reviewed; Journal article, 2020)
      The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified diagnostic technologies suitable for use in the field and for delivering ...

    • A multistep in vitro hemocompatibility testing protocol recapitulating the foreign body reaction to nanocarriers 

      Perugini, Valeria; Schmid, Ruth; Mørch, Ýrr Asbjørg; Texier, Isabelle; Brodde, Martin; Santin, Matteo (Peer reviewed; Journal article, 2022)
      The development of drug nanocarriers based on polymeric, lipid and ceramic biomaterials has been paving the way to precision medicine, where the delivery of poorly soluble active compounds and personalized doses are made ...

    • Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery 

      Mørch, Ýrr Asbjørg; Hansen, Rune; Berg, Sigrid; Åslund, Andreas; Glomm, Wilhelm; Eggen, Siv; Schmid, Ruth; Johnsen, Heidi; Kubowicz, Stephan; Snipstad, Sofie; Sulheim, Einar; Hak, Sjoerd; Singh, Gurvinder; McDonagh, Birgitte Hjelmeland; Blom, Hans; Davies, Ruth Catharina de Lange; Stenstad, Per Martin (Journal article; Peer reviewed, 2015)
      Microbubbles (MBs) are routinely used as contrast agents for ultrasound imaging. The use of ultrasound in combination with MBs has also attracted attention as a method to enhance drug delivery. We have developed a technology ...

    • Relationship between polarities of antibiotic and polymer matrix on nanoparticle formulations based on aliphatic polyesters 

      Ritsma, Jeffrey; Herschberg, E.M.A.; Borgos, Sven Even F.; Løvmo, Cathrine; Schmid, Ruth; Welscher, Y.M te; Storm, Gert; Nostrum, C.F. van (Journal article; Peer reviewed, 2017)

    • The solid progress of nanomedicine 

      Martins, Joao Pedro; Das Neves, José; de la Fuente, Maria; Celia, Christian; Florindo, Helena; Gunday-Tureli, Nazende; Popat, Amirali; Santos, Jose Luis; Sousa, Flavia; Schmid, Ruth; Wolfram, Joy; Sarmento, Bruno; Santos, Helder A. (Peer reviewed; Journal article, 2020)
      This commentary article conveys the views of the board of the Nanomedicine and Nanoscale Delivery Focus Group of the Controlled Release Society regarding the decision of the United States National Cancer Institute (NCI) ...

    • Sonopermeation to improve drug delivery to tumors: from fundamental understanding to clinical translation 

      Snipstad, Sofie; Sulheim, Einar; Davies, Catharina de Lange; Moonen, Chrit; Storm, Gert; Kiessling, Fabian; Schmid, Ruth; Lammers, Twan (Peer reviewed; Journal article, 2018)
      Introduction: Ultrasound in combination with microbubbles can make cells and tissues more accessible for drugs, thereby achieving improved therapeutic outcomes. In this review, we introduce the term ‘sonopermeation’, ...