Blar i SINTEF Open på forfatter "Tøndervik, Anne"
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Chitosan as a wound dressing starting material: antimicrobial Properties and mode of action
Matica, Mariana Adina; Aachmann, Finn Lillelund; Tøndervik, Anne; Sletta, Håvard; Ostafe, Vasile (Peer reviewed; Journal article, 2019)Fighting bacterial resistance is one of the concerns in modern days, as antibiotics remain the main resource of bacterial control. Data shows that for every antibiotic developed, there is a microorganism that becomes ... -
Exploiting mannuronan C-5 epimerases in commercial alginate production
Tøndervik, Anne; Aarstad, Olav Andreas; Aune, Randi; Maleki, Susan; Rye, Philip D; Dessen, Arne; Skjåk-Bræk, Gudmund; Sletta, Håvard (Peer reviewed; Journal article, 2020) -
High-throughput assay for effect screening of amphotericin B and bioactive components on filamentous Candida albicans
Haslene-Hox, Hanne; Nærdal, Guro Kruge; Mørch, Ýrr Asbjørg; Hageskal, Gunhild; Tøndervik, Anne; Vikenes, Anette; Johnsen, Heidi; Klinkenberg, Geir; Sletta, Håvard (Peer reviewed; Journal article, 2022) -
Identification of a Pivotal Residue for Determining the Block Structure-Forming Properties of Alginate C-5 Epimerases
Stanisci, Annalucia; Tøndervik, Anne; Gaardløs, Margrethe; Lervik, Anders; Skjåk-Bræk, Gudmund; Sletta, Håvard; Aachmann, Finn Lillelund (Peer reviewed; Journal article, 2020)Alginate is a linear copolymer composed of 1→4 linked β-d-mannuronic acid (M) and its epimer α-l-guluronic acid (G). The polysaccharide is first produced as homopolymeric mannuronan and subsequently, at the polymer level, ... -
Identification of Regulatory Genes and Metabolic Processes Important for Alginate Biosynthesis in Azotobacter vinelandii by Screening of a Transposon Insertion Mutant Library
Mærk, Mali; Jakobsen, Øyvind Mejdell; Sletta, Håvard; Klinkenberg, Geir; Tøndervik, Anne; Ellingsen, Trond Erling; Valla, Svein; Ertesvåg, Helga (Peer reviewed; Journal article, 2020)Azotobacter vinelandii produces the biopolymer alginate, which has a wide range of industrial and pharmaceutical applications. A random transposon insertion mutant library was constructed from A. vinelandii ATCC12518Tc in ... -
Molecular insights into alginate β-lactoglobulin A multivalencies—The foundation for their amorphous aggregates and coacervation
Madsen, Mikkel; Prestel, Andreas; Madland, Eva; Westh, Peter; Tøndervik, Anne; Sletta, Håvard; Peters, Günther H. J.; Aachmann, Finn Lillelund; Kragelund, Birthe B.; Svensson, Birte (Peer reviewed; Journal article, 2023)For improved control of biomaterial property design, a better understanding of complex coacervation involving anionic polysaccharides and proteins is needed. Here, we address the initial steps in condensate formation of ... -
Multiplex droplet digital PCR assay for detection of Flavobacterium psychrophilum and Yersinia ruckeri in Norwegian aquaculture
Lewin, Anna; Haugen, Tone; Netzer, Roman; Tøndervik, Anne; Dahle, Stine Veronica Wiborg; Hageskal, Gunhild (Peer reviewed; Journal article, 2020)We report the development of ddPCR assays for single and simultaneous detection of the bacterial pathogens Flavobacterium psychrophilum and Yersinia ruckeri in water from land-based recirculation aquaculture systems (RAS), ... -
Overall size of mannuronan C5-Epimerases influences their ability to epimerize modified alginates and alginate gels
Stanisci, Annalucia; Aarstad, Olav Andreas; Tøndervik, Anne; Sletta, Håvard; Dypås, Lene Brattsti; Skjåk-Bræk, Gudmund; Aachmann, Finn Lillelund (Peer reviewed; Journal article, 2018)A family of seven mannuronan C5-epimerases (AlgE1-AlgE7) produced by Azotobacter vinelandii is able to convert β-d-mannuronate (M) to its epimer α-l-guluronate (G) in alginates. Even sharing high sequence homology at the ... -
Strain Construction and Process Development for Efficient Recombinant Production of Mannuronan C-5 Epimerases in Hansenula polymorpha
Tøndervik, Anne; Aune, Randi; Degelmann, Adelheid; Piontek, Michael; Ertesvåg, Helga; Skjåk-Bræk, Gudmund; Sletta, Håvard (Peer reviewed; Journal article, 2022)Alginates are linear polysaccharides produced by brown algae and some bacteria and are composed of β-D-mannuronic acid (M) and α-L-guluronic acid (G). Alginate has numerous present and potential future applications within ...