Blar i Publikasjoner fra CRIStin - SINTEF AS på emneord "Nanomedicine"

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    • Asymmetric-flow field-flow fractionation for measuring particle size, drug loading and (in)stability of nanopharmaceuticals. The joint view of European Union Nanomedicine Characterization Laboratory and National Cancer Institute - Nanotechnology Characterization Laboratory 

      Caputo, Fanny; Mehn, Dora; Clogston, Jeffrey; Rösslein, Matthias; Prina-Mello, Adriele; Borgos, Sven Even F.; Gioria, Sabrina; Calzolai, Luigi (Peer reviewed; Journal article, 2021)
      Asymmetric-flow field-flow fractionation (AF4) has been recognized as an invaluable tool for the characterisation of particle size, polydispersity, drug loading and stability of nanopharmaceuticals. However, the application ...

    • Bridging communities in the field of nanomedicine 

      Halamoda-Kenzaoui, Blanka; Baconnier, Simon; Bastogne, Thierry; Bazile, Didier; Boisseau, Patrick; Borchard, Gerrit; Borgos, Sven Even F.; Calzolai, Luigi; Cederbrant, Karin; Di Felice, Gabriella; Di Francesco, Tiziana; Dobrovolskaia, Marina A.; Gaspar, Rogério; Gracia, Belén; Hackley, Vincent A.; Leyens, Lada; Liptrott, Neill; Park, Margriet; Patri, Anil; Roebben, Gert; Roesslein, Matthias; Thürmer, René; Urbán, Patricia; Zuang, Valérie; Bremer-Hoffmann, Susanne (Journal article; Peer reviewed, 2019)
      An early dialogue between nanomedicine developers and regulatory authorities are of utmost importance to anticipate quality and safety requirements for these innovative health products. In order to stimulate interactions between ...

    • A comparative biodistribution study of polymeric and lipid-based nanoparticles 

      Åslund, Andreas; Vandebriel, Rob J.; Caputo, Fanny; de Jong, Wim H.; Delmaar, Christiaan; Hyldbakk, Astrid; Rustique, Emilie; Schmid, Ruth Baumberger; Snipstad, Sofie; Texier, Isabelle; Vernstad, Kai; Borgos, Sven Even F. (Peer reviewed; Journal article, 2022)
      Biodistribution of nanoencapsulated bioactive compounds is primarily determined by the size, shape, chemical composition and surface properties of the encapsulating nanoparticle, and, thus, less dependent on the physicochemical ...

    • Delivering the power of nanomedicine to patients today 

      Germain, Matthieu; Caputo, Fanny; Metcalfe, Su; Tosi, Giovanni; Spring, Kathleen; Åslund, Andreas K.O.; Pottier, Agnes; Schiffelers, Raymond; Ceccaldi, Alexandre; Schmid, Ruth (Peer reviewed; Journal article, 2020)
      The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified diagnostic technologies suitable for use in the field and for delivering ...

    • Improved multidetector asymmetrical-flow field-flow fractionation method for particle sizing and concentration measurements of lipid-based nanocarriers for RNA delivery 

      Mildner, Robert; Hak, Sjoerd; Parot, Jeremie; Hyldbakk, Astrid; Borgos, Sven Even F.; some, dan; Johann, Cristoph; Caputo, Fanny (Peer reviewed; Journal article, 2021)
      Lipid-based nanoparticles for RNA delivery (LNP-RNA) are revolutionizing the nanomedicine field, with one approved gene therapy formulation and two approved vaccines against COVID-19, as well as multiple ongoing clinical ...

    • Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation 

      Halamoda-Kenzaoui, Blanka; Vandebriel, Rob; Howarth, Alice; Siccardi, Marco; David, Chris; Liptrott, Neill; Santin, Marco; Borgos, Sven Even F.; Bremer-Hoffmann, Susanne; Caputo, Fanny (Peer reviewed; Journal article, 2021)
      Nanotechnology-based health products are providing innovative solutions in health technologies and the pharmaceutical field, responding to unmet clinical needs. However, suitable standardised methods need to be available ...

    • The solid progress of nanomedicine 

      Martins, Joao Pedro; Das Neves, José; de la Fuente, Maria; Celia, Christian; Florindo, Helena; Gunday-Tureli, Nazende; Popat, Amirali; Santos, Jose Luis; Sousa, Flavia; Schmid, Ruth; Wolfram, Joy; Sarmento, Bruno; Santos, Helder A. (Peer reviewed; Journal article, 2020)
      This commentary article conveys the views of the board of the Nanomedicine and Nanoscale Delivery Focus Group of the Controlled Release Society regarding the decision of the United States National Cancer Institute (NCI) ...

    • Sonopermeation Enhances Uptake and Therapeutic Effect of Free and Encapsulated Cabazitaxel 

      Snipstad, Sofie; Mørch, Ýrr; Sulheim, Einar; Åslund, Andreas; Pedersen, André; Hansen, Rune; Davies, Catharina de Lange; Berg, Sigrid (Peer reviewed; Journal article, 2021)
      Delivery of drugs and nanomedicines to tumors is often heterogeneous and insufficient and, thus, of limited efficacy. Microbubbles in combination with ultrasound have been found to improve delivery to tumors, enhancing ...