• Computational and Experimental Druggability Assessment of Human DNA Glycosylases 

      Michel, M; Visnes, Torkild; Homan, Evert; Seashore-Ludlow, Brinton; Hedenström, Mattias; Wiita, Elisee; Vallin, K; Paulin, Cynthia BJ; Zhang, Jiaxi; Wallner, Olov; Scobie, Martin; Schmidt, A.; Jenmalm-Jensen, Annika; Warpman Berglund, Ulrika; Helleday, Thomas (Peer reviewed; Journal article, 2019)
      Due to a polar or even charged binding interface, DNA-binding proteins are considered extraordinarily difficult targets for development of small-molecule ligands and only a handful of proteins have been targeted successfully ...