Blar i SINTEF Industri på tidsskrift "Journal of Controlled Release"

Viser treff 1-8 av 8

    • Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft. 

      Fusser, Markus; Øverbye, Anders; Pandya, Abhilash D.; Mørch, Ýrr Asbjørg; Borgos, Sven Even F.; Kildal, Wanja; Snipstad, Sofie; Sulheim, Einar; Fleten, Karianne Giller; Askautrud, Hanne Arenberg; Engebraaten, Olav; Flatmark, Kjersti; Iversen, Tore Geir; Sandvig, Kirsten; Skotland, Tore; Mælandsmo, Gunhild Mari (Journal article; Peer reviewed, 2018)

    • Delivering the power of nanomedicine to patients today 

      Germain, Matthieu; Caputo, Fanny; Metcalfe, Su; Tosi, Giovanni; Spring, Kathleen; Åslund, Andreas K.O.; Pottier, Agnes; Schiffelers, Raymond; Ceccaldi, Alexandre; Schmid, Ruth (Peer reviewed; Journal article, 2020)
      The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified diagnostic technologies suitable for use in the field and for delivering ...

    • Effect of acoustic cluster therapy (ACT®) combined with chemotherapy in a patient-derived xenograft mouse model of pancreatic cancer 

      Ng, Serina; Healey, Andrew J.; Sontum, Per Christian; Kvåle, Svein; Torp, Sverre Helge; Sulheim, Einar; Von Hoff, Daniel; Han, Haiyoung (Peer reviewed; Journal article, 2022)
      Pancreatic ductal adenocarcinomas respond poorly to chemotherapy, in part due to the dense tumor stroma that hinders drug delivery. Ultrasound (US) in combination with microbubbles has previously shown promise as a means ...

    • Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation 

      Halamoda-Kenzaoui, Blanka; Vandebriel, Rob; Howarth, Alice; Siccardi, Marco; David, Chris; Liptrott, Neill; Santin, Marco; Borgos, Sven Even F.; Bremer-Hoffmann, Susanne; Caputo, Fanny (Peer reviewed; Journal article, 2021)
      Nanotechnology-based health products are providing innovative solutions in health technologies and the pharmaceutical field, responding to unmet clinical needs. However, suitable standardised methods need to be available ...

    • Methodological needs in the quality and safety characterisation of nanotechnology-based health products: Priorities for method development and standardisation 

      Halamoda-Kenzaoui, Blanka; Vandebriel, Rob; Howarth, Alice; Siccardi, Marco; David, Chris; Liptrott, Neill; Santin, Marco; Borgos, Sven Even F.; Bremer-Hoffmann, Susanne; Caputo, Fanny (Peer reviewed; Journal article, 2021)
      Nanotechnology-based health products are providing innovative solutions in health technologies and the pharmaceutical field, responding to unmet clinical needs. However, suitable standardised methods need to be available ...

    • Multi-modal characterization of vasculature and nanoparticle accumulation in five tumor xenograft models 

      Sulheim, Einar; Kim, Jana; van Wamel, Annemieke; Kim, Eugene; Snipstad, Sofie; Vidic, Igor; Grimstad, Ingeborg; Widerøe, Marius; Torp, Sverre Helge; Lundgren, Steinar; Waxman, David J.; Davies, Catharina de Lange (Peer reviewed; Journal article, 2018)
      Preclinical research has demonstrated that nanoparticles and macromolecules can accumulate in solid tumors due to the enhanced permeability and retention effect. However, drug loaded nanoparticles often fail to show increased ...

    • Targeted siRNA lipid nanoparticles for the treatment of KRAS-mutant tumors 

      Anthiya, Shubaash; Oztürk, Süleyman Can; Yanik, Hamdullah; Tavukcuoglu, Ece; Sahin, Adem; Datta, Dhrubajyoti; Charisse, Klaus; Álvarez, David Moreira; Loza, María Isabel; Calvo, Alfonso; Sulheim, Einar; Loevenich, Simon; Klinkenberg, Geir; Schmid, Ruth Baumberger; Manoharan, Muthiah; Esendağlı, Güneş; Jose Alonso, Maria (Peer reviewed; Journal article, 2023)
      K-RAS is a highly relevant oncogene that is mutated in approximately 90% of pancreatic cancers and 20–25% of lung adenocarcinomas. The aim of this work was to develop a new anti-KRAS siRNA therapeutic strategy through the ...

    • Ultrasound-mediated delivery enhances therapeutic efficacy of MMP sensitive liposomes 

      Olsman, Marieke; Sereti, Viktoria; Andreassen, Kristine; Snipstad, Sofie; van Wamel, Annemieke; Eliasen, Rasmus; Berg, Sigrid; Urquhart, Andrew J.; Andersen, Thomas L.; Davies, Catharina de Lange (Peer reviewed; Journal article, 2020)
      To improve therapeutic efficacy of nanocarrier drug delivery systems, it is essential to improve their uptake and penetration in tumour tissue, enhance cellular uptake and ensure efficient drug release at the tumour site. ...