• Cytotoxicity of poly(Alkyl cyanoacrylate) nanoparticles 

      Sulheim, Einar; Iversen, Tore Geir; To, Vu; Klinkenberg, Geir; Sletta, Håvard; Schmid, Ruth; Hatletveit, Anne Rein; Wågbø, Ane Marit; Sundan, Anders; Skotland, Tore; Sandvig, Kirsten; Mørch, Ýrr Asbjørg (Peer reviewed; Journal article, 2017)
      Although nanotoxicology has become a large research field, assessment of cytotoxicity is often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and should, preferentially, be evaluated ...
    • Identification of novel cyanoacrylate monomers for use in nanoparticle drug delivery systems prepared by miniemulsion polymerisation – A multistep screening approach 

      Hyldbakk, Astrid; Mørch, Ýrr Asbjørg; Snipstad, Sofie; Åslund, Andreas; Klinkenberg, Geir; Nakstad, Vu; Wågbø, Ane Marit; Schmid, Ruth Baumberger; Molesworth, Peter Patrick (Peer reviewed; Journal article, 2022)
      Poly (alkyl cyanoacrylate) (PACA) polymeric nanoparticles (NPs) are promising drug carriers in drug delivery. However, the selection of commercially available alkyl cyanoacrylate (ACA) monomers is limited, because most ...
    • Interlaboratory evaluation of a digital holographic microscopy–based assay for label-free in vitro cytotoxicity testing of polymeric nanocarriers 

      Marzi, Anne; Eder, Kai Moritz; Barroso, Álvaro; Wågbø, Ane Marit; Mørch, Ýrr Asbjørg; Hatletveit, Anne Rein; Visnes, Torkild; Schmid, Ruth Baumberger; Klinkenberg, Geir; Kemper, Björn; Schnekenburger, Jürgen (Peer reviewed; Journal article, 2022)
      State-of-the-art in vitro test systems for nanomaterial toxicity assessment are based on dyes and several staining steps which can be affected by nanomaterial interference. Digital holographic microscopy (DHM), an ...
    • Magnetic-Responsive Carbon Nanotubes Composite Scaffolds for Chondrogenic Tissue Engineering 

      Saranya, Muthusamy; da Silva, Aldeliane M.; Karjalainen, Hanna; Klinkenberg, Geir; Schmid, Ruth Baumberger; McDonagh, Birgitte Hjelmeland; Molesworth, Peter Patrick; Sigfúsdóttir, Margrét S.; Wågbø, Ane Marit; Santos, Susana. G.; Couto, Cristiana; Karjalainen, Ville-Pauli; Gupta, Shuvashis Das; Järvinen, Topias; de Roy, Luisa; Seitz, Andreas. M.; Finnilä, Mikko; Saarakkala, Simo; Haaparanta, Anne Marie; Janssen, Lauriane; Lorite, Gabriela S. (Peer reviewed; Journal article, 2023)
      The demand for engineered scaffolds capable of delivering multiple cues to cells continues to grow as the interplay between cell fate with microenvironmental and external cues is revealed. Emphasis has been given to develop ...
    • Standardization of an in vitro assay matrix to assess cytotoxicity of organic nanocarriers: a pilot interlaboratory comparison 

      Eder, Kai Moritz; Marzi, Anne; Wågbø, Ane Marit; Vermeulen, Jolanda P.; de la Fonteyne-Blankestijn, Liset J. J.; Rösslein, Matthias; Ossig, Rainer; Klinkenberg, Geir; Vandebriel, Rob J.; Schnekenburger, Jürgen (Peer reviewed; Journal article, 2022)
      Nanotechnologies such as nanoparticles are established components of new medical devices and pharmaceuticals. The use and distribution of these materials increases the requirement for standardized evaluation of possible ...