• Effect of ultrasound on the vasculature and extravasation of nanoscale particles imaged in real time 

      Yemane, Petros Tesfamichael; Åslund, Andreas K. O.; Snipstad, Sofie; Bjørkøy, Astrid; Grendstad, Kristin; Berg, Sigrid; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Hansen, Rune; Davies, Catharina de Lange (Journal article; Peer reviewed, 2019)
      Ultrasound and microbubbles have been found to improve the delivery of drugs and nanoparticles to tumor tissue. To obtain new knowledge on the influence of vascular parameters on extravasation and to elucidate the effect ...
    • Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking 

      Sofias, Alexandros Marios; Toner, Yohana C.; Meerwaldt, Anu E.; van Leent, Mandy M. T.; Soultanidis, Georgios; Elschot, Mattijs; Gonai, Haruki; Grendstad, Kristin; Flobak, Åsmund; Neckmann, Ulrike; Wolowczyk, Camilla; Fisher, Elizabeth L.; Reiner, Thomas; Davies, Catharina de Lange; Bjørkøy, Geir; Teunissen, Abraham J. P.; Ochando, Jordi; Pérez-Medina, Carlos; Mulder, Willem J. M.; Hak, Sjoerd (Peer reviewed; Journal article, 2020)
      Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...