Browsing SINTEF Open by Author "Davies, Ruth Catharina de Lange"

Now showing items 1-3 of 3

    • Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery 

      Mørch, Ýrr Asbjørg; Hansen, Rune; Berg, Sigrid; Åslund, Andreas; Glomm, Wilhelm; Eggen, Siv; Schmid, Ruth; Johnsen, Heidi; Kubowicz, Stephan; Snipstad, Sofie; Sulheim, Einar; Hak, Sjoerd; Singh, Gurvinder; McDonagh, Birgitte Hjelmeland; Blom, Hans; Davies, Ruth Catharina de Lange; Stenstad, Per Martin (Journal article; Peer reviewed, 2015)
      Microbubbles (MBs) are routinely used as contrast agents for ultrasound imaging. The use of ultrasound in combination with MBs has also attracted attention as a method to enhance drug delivery. We have developed a technology ...

    • Primary Porcine Brain Endothelial Cells as In Vitro Model to Study Effects of Ultrasound and Microbubbles on Blood-Brain Barrier Function 

      Lelu, Sylvie; Afadzi, Mercy; Berg, Sigrid; Åslund, Andreas; Torp, Sverre Helge; Sattler, Wolfgang; Davies, Ruth Catharina de Lange (Journal article; Peer reviewed, 2017)
      Focused ultrasound (FUS) in the presence of microbubbles transiently and reversibly opens the blood-brain barrier (BBB) in rodents and humans, thereby providing a time window for increased drug delivery into brain tissue. ...

    • Ultrasound Improves the Delivery and Therapeutic Effect of Nanoparticle-Stabilized Microbubbles in Breast Cancer Xenografts 

      Snipstad, Sofie; Berg, Sigrid; Mørch, Ýrr Asbjørg; Bjørkøy, Astrid; Sulheim, Einar; Hansen, Rune; Grimstad, Ingeborg; van Wamel, Annemieke; Maaland, Astri Fjelde; Torp, Sverre Helge; Davies, Ruth Catharina de Lange (Peer reviewed; Journal article, 2017)
      Compared with conventional chemotherapy, encapsulation of drugs in nanoparticles can improve efficacy and reduce toxicity. However, delivery of nanoparticles is often insufficient and heterogeneous because of various ...