Browsing SINTEF Open by Author "Bjørkøy, Astrid"
Now showing items 1-4 of 4
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Effect of ultrasound on the vasculature and extravasation of nanoscale particles imaged in real time
Yemane, Petros Tesfamichael; Åslund, Andreas K. O.; Snipstad, Sofie; Bjørkøy, Astrid; Grendstad, Kristin; Berg, Sigrid; Mørch, Ýrr Asbjørg; Torp, Sverre Helge; Hansen, Rune; Davies, Catharina de Lange (Journal article; Peer reviewed, 2019)Ultrasound and microbubbles have been found to improve the delivery of drugs and nanoparticles to tumor tissue. To obtain new knowledge on the influence of vascular parameters on extravasation and to elucidate the effect ... -
Sonoporation using nanoparticle-loaded microbubbles increases cellular uptake of nanoparticles compared to co-incubation of nanoparticles and microbubbles
Snipstad, Sofie; Hanstad, Sigurd; Bjørkøy, Astrid; Mørch, Ýrr Asbjørg; Davies, Catharina de Lange (Peer reviewed; Journal article, 2021)Therapeutic agents can benefit from encapsulation in nanoparticles, due to improved pharmacokinetics and biodistribution, protection from degradation, increased cellular uptake and sustained release. Microbubbles in ... -
The Effect of Sonication on Extravasation and Distribution of Nanoparticles and Dextrans in Tumor Tissue Imaged by Multiphoton Microscopy
Yemane, Petros Tesfamichael; Åslund, Andreas; Sæterbø, Kristin Grendstad; Bjørkøy, Astrid; Snipstad, Sofie; van Wamel, Annemieke; Berg, Sigrid; Mørch, Ýrr Asbjørg; Hansen, Rune; Angelsen, Bjørn Atle Johan; Davies, Catharina de Lange (Journal article; Peer reviewed, 2018)Ultrasound (US)and systemic administration of microbubbles (MBs)have been shown to improve the delivery of drugs and nanoparticles (NPs)to tumor tissue. A better understanding of the mechanisms is crucial for effective ... -
Ultrasound Improves the Delivery and Therapeutic Effect of Nanoparticle-Stabilized Microbubbles in Breast Cancer Xenografts
Snipstad, Sofie; Berg, Sigrid; Mørch, Ýrr Asbjørg; Bjørkøy, Astrid; Sulheim, Einar; Hansen, Rune; Grimstad, Ingeborg; van Wamel, Annemieke; Maaland, Astri Fjelde; Torp, Sverre Helge; Davies, Ruth Catharina de Lange (Peer reviewed; Journal article, 2017)Compared with conventional chemotherapy, encapsulation of drugs in nanoparticles can improve efficacy and reduce toxicity. However, delivery of nanoparticles is often insufficient and heterogeneous because of various ...