• A new acoustic coupling fluid with ability to reduce ultrasound imaging artefacts in brain tumour surgery - a phase I study 

      Unsgård, Geirmund; Sagberg, Lisa Millgård; Muller, Sebastien; Selbekk, Tormod (Journal article; Peer reviewed, 2019)
      Background Anovel acoustic coupling fluid (ACF), with the potential to reduce surgically induced image artefacts during intraoperative ultrasound imaging in brain tumour surgery, has been evaluated with respect to image ...
    • Animal study assessing safety of an acoustic coupling fluid that holds the potential to avoid surgically induced artifacts in 3D ultrasound guided operations 

      Jakola, Asgeir S; Jørgensen, Arve; Selbekk, Tormod; Michler, Ralf-Peter; Solheim, Ole; Torp, Sverre Helge; Sagberg, Lisa Millgård; Aadahl, Petter; Unsgård, Geirmund (Journal article; Peer reviewed, 2014)
      Background Use of ultrasound in brain tumor surgery is common. The difference in attenuation between brain and isotonic saline may cause artifacts that degrade the ultrasound images, potentially affecting resection grades ...
    • Are there predilection sites for intracranial meningioma? A population-based atlas 

      Hosainey, Sayied Abdol Mohieb; Bouget, David; Reinertsen, Ingerid; Sagberg, Lisa Millgård; Torp, Sverre Helge; Jakola, Asgeir Store; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Meningioma is the most common benign intracranial tumor and is believed to arise from arachnoid cap cells of arachnoid granulations. We sought to develop a population-based atlas from pre-treatment MRIs to explore the ...
    • Brain atlas for assessing the impact of tumor location on perioperative quality of life in patients with high-grade glioma: A prospective population-based cohort study 

      Sagberg, Lisa Millgård; Iversen, Daniel Høyer; Fyllingen, Even Hovig; Jakola, Asgeir Store; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2019)
      Background Tumor location is important for surgical decision making. Particular attention is paid to regions that contain sensorimotor and language functions, but it is unknown if these are the most important regions from ...
    • Glioblastoma Surgery Imaging-Reporting and Data System: Validation and Performance of the Automated Segmentation Task 

      Bouget, David Nicolas Jean-Marie; Eijgelaar, Roelant; Pedersen, André; Kommers, Ivar; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Nibali, Marco Conti; Furtner, Julia; Fyllingen, Even Hovig; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Kloet, Alfred; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre; Rossi, Marco; Sagberg, Lisa Millgård; Sciortino, Tommaso; van den Brink, Wimar A.; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Reinertsen, Ingerid; Hamer, Philip C De Witt; Solheim, Ole (Peer reviewed; Journal article, 2021)
      For patients with presumed glioblastoma, essential tumor characteristics are determined from preoperative MR images to optimize the treatment strategy. This procedure is time-consuming and subjective, if performed by crude ...
    • Glioblastoma Surgery Imaging—Reporting and Data System: Standardized Reporting of Tumor Volume, Location, and Resectability Based on Automated Segmentations 

      Kommers, Ivar; Bouget, David Nicolas Jean-Marie; Pedersen, André; Eijgelaar, Roelant; Ardon, Hilko; Barkhof, Frederik; Bello, Lorenzo; Berger, Mitchel S.; Nibali, Marco Conti; Furtner, Julia; Fyllingen, Even Hovig; Hervey-Jumper, Shawn; Idema, Albert J. S.; Kiesel, Barbara; Kloet, Alfred; Mandonnet, Emmanuel; Müller, Domenique M. J.; Robe, Pierre; Rossi, Marco; Sagberg, Lisa Millgård; Sciortino, Tommaso; van den Brink, Wimar A.; Wagemakers, Michiel; Widhalm, Georg; Witte, Marnix G.; Zwinderman, Aeilko H.; Reinertsen, Ingerid; Solheim, Ole; De Witt Hamer, Philip C. (Peer reviewed; Journal article, 2021)
      Treatment decisions for patients with presumed glioblastoma are based on tumor characteristics available from a preoperative MR scan. Tumor characteristics, including volume, location, and resectability, are often estimated ...
    • How well do neurosurgeons predict survival in patients with high-grade glioma? 

      Sagberg, Lisa Millgård; Jakola, Asgeir S.; Reinertsen, Ingerid; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Due to the lack of reliable prognostic tools, prognostication and surgical decisions largely rely on the neurosurgeons’ clinical prediction skills. The aim of this study was to assess the accuracy of neurosurgeons’ prediction ...
    • Pretreatment patient-reported cognitive function in patients with diffuse glioma 

      Schei, Stine; Solheim, Ole; Salvesen, Øyvind; Hjermstad, Marianne Jensen; Bouget, David Nicolas Jean-Marie; Sagberg, Lisa Millgård (Peer reviewed; Journal article, 2022)
      Purpose: Cognitive function is frequently assessed with objective neuropsychological tests, but patient-reported cognitive function is less explored. We aimed to investigate the preoperative prevalence of patient-reported ...
    • Spatial distribution of malignant transformation in patients with low-grade glioma 

      Jakola, Asgeir S; Bouget, David Nicolas Jean-Marie; Reinertsen, Ingerid; Skjulsvik, Anne Jarstein; Sagberg, Lisa Millgård; Bø, Hans Kristian; Gulati, Sasha; Sjåvik, Kristin; Solheim, Ole (Peer reviewed; Journal article, 2020)
      Background Malignant transformation represents the natural evolution of diffuse low-grade gliomas (LGG). This is a catastrophic event, causing neurocognitive symptoms, intensified treatment and premature death. However, ...
    • Survival of glioblastoma in relation to tumor location: a statistical tumor atlas of a population-based cohort 

      Fyllingen, Even Hovig; Bø, Lars Eirik; Reinertsen, Ingerid; Jakola, Asgeir Store; Sagberg, Lisa Millgård; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole (Peer reviewed; Journal article, 2021)
      Purpose: Previous studies on the effect of tumor location on overall survival in glioblastoma have found conflicting results. Based on statistical maps, we sought to explore the effect of tumor location on overall survival ...
    • The diagnostic properties of intraoperative ultrasound in glioma surgery and factors associated with gross total tumor resection 

      Munkvold, Bodil Karoline Ravn; Jakola, Asgeir Store; Reinertsen, Ingerid; Sagberg, Lisa Millgård; Unsgård, Geirmund; Solheim, Ole (Journal article; Peer reviewed, 2018)
      Objective In glioma operations, we sought to analyze sensitivity, specificity, and predictive values of intraoperative 3-dimensional ultrasound (US) for detecting residual tumor compared with early postoperative magnetic ...